Wendy Wei-Lynn Wong
University of Zurich, Switzerland
Inhibitors of Apoptosis proteins in disease and inflammation
Our laboratory investigates how cell death proteins may regulate signaling downstream of TNFR2 in different stromal and immune compartments. In particular, we investigate the effect of targeting cell death proteins will have in tumor extravasation, endothelial cell permeability and immune cell differentiation and function. We anticipate the molecular understanding of how and when cell death proteins directly regulate inflammation will lead to novel targets in reducing acute or chronic inflammation.